Sildenafil and dapoxetine are combined in Super P-Force tablets 100mg/60mg to treat erectile dysfunction and premature ejaculation. Sildenafil in Super P-Force tablets increases blood flow to the erectile tissue of the penis, causing an erection. Nitric oxide is released in the erectile tissue of the penis during sexual stimulation, which activates the enzyme guanylate cyclase.
This enzyme causes an erection by increasing the levels of a chemical called cyclic guanosine monophosphate (cGMP), which relaxes the blood vessels in the penis and allows blood to fill the spongy erectile tissues.
Dapoxetine, which is found in super pforce tablets, is an antidepressant known as a selective serotonin reuptake inhibitor (SSRI). Dapoxetine, on the other hand, was created specifically for the treatment of premature ejaculation because it has a fast onset of action, a maximum effect in 1-2 hours, and a short half-life, meaning it is quickly eliminated from the body within 24 hours.
Phosphodiesterase type 5 (PDE5) is another enzyme that breaks down cGMP, preventing blood flow into the penis and causing erection loss.
The action of PDE5 is inhibited by sildenafil in Super P-Force tablets, which resolves erectile dysfunction by allowing the natural process of sexual stimulation to activate the cGMP mechanism for achieving and maintaining an erection.
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